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Lichen sclerosus et atrophicus and autoimmunity—a study of 350 women
Author(s) -
THOMAS R.H.MEYRICK,
RIDLEY C.M.,
MCGIBBON D.H.,
BLACK M.M.
Publication year - 1988
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1988.tb01748.x
Subject(s) - lichen sclerosus , autoimmune disease , autoantibody , autoimmunity , medicine , immunology , dermatology , antibody
summary A study of autoimmune related phenomena in 350 women with histologically confirmed lichen sclerosus et atrophicus revealed that 21.5% had one or more autoimmune related diseases, 21% had one or more first degree relatives with an autoimmune‐related disease, 42% had an autoantibody at a titre > 1:20, and 59.5% had one or more of these autoimmune‐relateda phenomena. No statistically significant differences in the natural history of lichen sclerosus et atrophicus were demonstrated between those patients with autoimmune‐related phenomena and those without.