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Cutaneous presentation of malignant fibrous histiocytoma
Author(s) -
GrahamBrown R.A.C.,
Fletcher A.
Publication year - 1987
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1987.tb11998.x
Subject(s) - presentation (obstetrics) , medicine , dermatology , library science , surgery , computer science
We have reviewed the clinical and pathological details of 10 patients with malignant fibrous histiocytoma (MFH) recorded in the diagnostic index of our pathology department computer between January 1983 and January 1986. There were seven males and three females in the series, age range of 55–82 years, average age 74 years. One patient had a lesion in the testis. Five presented with subcutaneous masses, three on the limbs, one on the neck and one on the upper back. Four patients presented with cutaneous lesions. In one, a mass arose in an area previously treated with radiotherapy. The remaining three had lower leg ulceration and there was a clear preceding history of varicose veins and ulceration in two, and a history of trauma to the affected leg in two. All the tumours were of the pleomorphic/spindle cell histological variant except one, affecting the right calf, which had a myxoid pathology. MFH is said to be the commonest soft tissue sarcoma of later life. 1 There are isolated reports of cutaneous tumours, especially in post‐irradiated areas. To our knowledge there has been only one report of the tumour in relation to chronic ulceration. 2 Dermatologists should be aware of this important tumour and its modes of presentation.