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Beneficial effects of danazol on symptoms and laboratory changes in cholinergic urticaria
Author(s) -
WONG ELIZABETH,
EFTEKHARI N.,
GREAVES M.W.,
WARD A. MILFORD
Publication year - 1987
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1987.tb05877.x
Subject(s) - danazol , medicine , cholinergic , placebo , cholinergic fibers , dermatology , pathology , endometriosis , alternative medicine , cholinergic neuron
SUMMARY In a double‐blind placebo‐controlled study, danazol, an attenuated androgen, was effective in reducing exercise‐induced weals in cholinergic urticaria. Danazol treatment also caused significant elevations of several protease inhibitors, particularly antichymotrypsin which has been reported previously to be low in cholinergic urticaria.