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Enhancement of Candida albicans killing activity of separated human epidermal cells by ultraviolet radiation
Author(s) -
CSATO M.,
KENDERESSY ANNA SZ.,
DOBOZY A.
Publication year - 1987
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1987.tb05864.x
Subject(s) - candida albicans , microbiology and biotechnology , ultraviolet radiation , ultraviolet , chemistry , biology , materials science , radiochemistry , optoelectronics
SUMMARY Ultraviolet irradiation enhanced the Candida albicans killing activity of freshly separated human epidermal cells in vitro. The stimulation was dose‐dependent and was not due to soluble extracellular factors acting on non‐irradiated epidermal cells. The enhancement of the killing activity remained unchanged when epidermal cells were depleted of Langerhans cells. Protein synthesis inhibitors and prostaglandin antagonists abrogated the ultraviolet‐induced augtnentation of killing activity.