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Anhidrotic and achromians lesions in incontinentia pigmenti
Author(s) -
MOSS CELIA,
INCE P.
Publication year - 1987
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1987.tb04903.x
Subject(s) - incontinentia pigmenti , hairless , ectodermal dysplasia , dermatology , abnormality , sign (mathematics) , medicine , genodermatosis , dysplasia , pathology , audiology , genetics , biology , mathematical analysis , mathematics , psychiatry , gene
SUMMARY Three women subsequently shown to have incontinentia pigmenti (IP) presented with white hairless streaks on the limbs as the predominant cutaneous abnormality. Seven other patients with IP diagnosed in infancy were reviewed to establish the frequency of this sign. It was found in all of them, and in the otherwise unaffected mother of three affected girls. A focal absence of sweating in these lesions is reported here for the first time. There are other similarities with anhidrotic ectodermal dysplasia, suggesting a genetic overlap between these two X‐linked conditions.