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Magnetic resonance imaging as a screening procedure for methotrexate induced liver damage
Author(s) -
RADEMAKER M.,
WEBB J.A.W.,
LOWE D.G.,
MEYRICKTHOMAS R.H.,
KIRBY J.D.T.,
MUNRO D.D.
Publication year - 1987
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1987.tb04137.x
Subject(s) - methotrexate , psoriasis , magnetic resonance imaging , medicine , liver fibrosis , nuclear magnetic resonance , materials science , pathology , fibrosis , radiology , physics , dermatology
SUMMARY Spin lattice relaxation time (T i ) measured with a low field strength magnetic resonance imager in 51 patients with severe psoriasis did not correlate with the histological findings of liver biopsies taken during treatment with oral methotrexate. Liver T i measurement at low magnetic field is of no value as a screening procedure in monitoring methotrexate induced liver damage.