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Generalized pustular psoriasis precipitated by trazodone in the treatment of depression
Author(s) -
BARTH J.H.,
BAKER H.
Publication year - 1986
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1986.tb05776.x
Subject(s) - trazodone , psoriasis , medicine , depression (economics) , dermatology , generalized pustular psoriasis , lithium (medication) , antagonist , pustular psoriasis , antidepressant , receptor , macroeconomics , economics , hippocampus
SUMMARY Severe psoriasis is commonly associated with depression and may be its cause. The hazards of treating such patients with lithium are well known (Lazarus & Gilgor, 1979), but other drugs may also destabilize psoriasis. We report a patient in whom the anti‐depressant trazodone hydrochloride (Molipaxin®, Roussel), a serotonin antagonist, provoked generalized pustular psoriasis (GPP).