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Discoid lupus erythematosus‐like lesions in an autosomal form of chronic granulomatous disease
Author(s) -
STALDER J.F.,
DRENO B.,
BUREAU B.,
HAKIM J.
Publication year - 1986
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1986.tb02805.x
Subject(s) - chronic granulomatous disease , medicine , systemic lupus erythematosus , disease , immunology , lupus erythematosus , dermatology , pathology , antibody
SUMMARY Chronic granulomatous disease (CGD) is characterized by a bactericidal defect involving the oxidative metabolism of polymorphonuclear leukocytes (PML) and is most often transmitted as an X‐linked trait. The cutaneous features of this disorder include infections and lupus‐like rashes. These have been described in female carriers as well as in males with the disease. Two cases of siblings presenting an autosomal form of CGD syndrome, with lupus‐like cutaneous manifestations, are reported here.