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Haemorrhagic pompholyx as a sign of bullous pemphigoid and as an indication for low‐dose prednisolone therapy
Author(s) -
Barth J.H.,
Fairris G.M.,
Wojnarowska F.,
White J.E.
Publication year - 1985
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1985.tb13010.x
Subject(s) - bullous pemphigoid , medicine , prednisolone , dapsone , dermatology , pemphigoid , differential diagnosis , sign (mathematics) , surgery , pathology , immunology , mathematical analysis , antibody , mathematics
Four patients are described who presented with haemorrhagic pompholyx as a sign of bullous pemphigoid. Three of these patients initially had lesions localized to the hands and feet. The diagnosis of bullous pemphigoid was made by histopathological and immunofluorescent examination. All four patients have responded well to low‐dose prednisolone (20 mg) therapy. Localized pemphigoid has been reported simulating pompholyx in a case in which the unusual presentation delayed the diagnosis. The disease was easily controlled with dapsone and remitted after 4 months therapy (Levine et al. , 1979). These cases stress the need to consider bullous pemphigoid in the differential diagnosis of haemorrhagic pompholyx and that this physical sign suggests a good response to low‐dose steroids.