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Distribution of ATPase‐positive Langerhans cells in normal adult human skin
Author(s) -
CHEN H.,
YUAN J.,
WANG Y.,
SILVERS W.K.
Publication year - 1985
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1985.tb02406.x
Subject(s) - distribution (mathematics) , langerhans cell , medicine , pathology , dermatology , biology , immunology , antigen , mathematics , mathematical analysis
SUMMARY The distribution of ATPase‐positive Langerhans cells (LC) was investigated in 117 specimens of normal adult human skin and mucosa taken from different areas of the body. Although there were significant variations in the numbers of LC in each area examined, skin from the face and neck contained the highest density of cells (976±30.93/mm 2 ). The densities of LC in trunk skin (740±28.97/mm 2 ), scalp (693±69.56/mm 2 ) and arm or leg skin (640±40.95/mm 2 ) were similar. Buccal mucosa had significantly fewer LC (567±42.94/mm 2 ) than trunk skin, and sacrococcyx skin and palm and sole skin displayed the smallest number of these cells (267±56.14/mm 2 and, 189±19.15/mm 2 respectively). No ATPase‐positive LC were detected in the centre of two corneal specimens.