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The effect of steroid sulphatase on stratum corneum shedding in patients with X‐linked ichthyosis
Author(s) -
YOSHIIKE T.,
MATSUI T.,
KIMURA T.,
YAMADA H.,
OGAWA H.
Publication year - 1985
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1985.tb02398.x
Subject(s) - stratum corneum , ichthyosis , steroid sulfatase , steroid , ichthyosis vulgaris , dermatology , dyskeratosis , stratum , lamellar ichthyosis , chemistry , medicine , endocrinology , filaggrin , hyperkeratosis , biology , atopic dermatitis , pathology , hormone , paleontology
SUMMARY After the application under occlusion of partially purified stratum corneum steroid sulphatase to the skin of patients with X‐linked ichthyosis, the detachment ratio of stratum corneum fragments was significantly increased. There was no significant change in normal subjects or in patients with ichthyosis vulgaris.