Premium
Epidermolytic variant of hereditary palmoplantar keratoderma
Author(s) -
CAMISA CHARLES,
WILLIAMS HOMER
Publication year - 1985
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1985.tb00087.x
Subject(s) - epidermolytic hyperkeratosis , palmoplantar keratoderma , dermatology , keratoderma , medicine , isotretinoin , hyperkeratosis , dyskeratosis , keratolytic , pathology , skin biopsy , biopsy , acne
SUMMARY The seventh family with autosomal dominant epidermolytic palmoplantar keratoderma is reported. The lesions are clinically indistinguishable from Unna‐Thost disease but resemble epidermolytic hyperkeratosis (bullous ichthyroderma) histopathologically. A skin biopsy is essential for making the correct diagnosis. One of our patients was treated with isotretinoin for 13 weeks without significant improvement.