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Mechanisms of pustule formation in cutaneous bacterial and viral infections: alterations of neutrophil membrane surface receptors
Author(s) -
IMAIZUMI S.,
IWATSUKI K.,
YAMADA M.,
TAGAMI H.
Publication year - 1984
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1984.tb07460.x
Subject(s) - receptor , cell surface receptor , immunology , viral infection , biology , microbiology and biotechnology , chemistry , virology , virus , biochemistry
SUMMARY Changes in membrane surface receptors have been demonstrated by rosetting methods in polymorphonuclear leukocytes obtained from the pustules of different infectious dermatoses. There was a distinct difference in numbers of receptors in neutrophils from bacterial and viral pustules, i.e., C 3 b receptors were decreased on neutrophils from both bacterial and viral pustules, whereas IgG‐Fc receptors were decreased only in neutrophils from viral pustules. The difference appears to be due to variations in the defence mechanisms against the invading micro‐organisms.