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Dermal elastosis in hairless mice after UV‐B and UV‐A applied simultaneously, separately or sequentially
Author(s) -
POULSEN J.T.,
STABERG B.,
WULF H.C.,
BRODTHAGEN H.
Publication year - 1984
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1984.tb04675.x
Subject(s) - hairless , dermis , irradiation , chemistry , ultraviolet b , dermatology , epidermis (zoology) , pathology , medicine , anatomy , biochemistry , physics , nuclear physics
SUMMARY The elastosis‐inducing capacity of UV‐A and UV‐B was studied in the skin of hairless mice. After irradiation with UV‐B and UV‐A applied either simultaneously, separately or sequentially, the degree of elastosis in the dermis was microscopically evaluated. This semi‐quantitative method showed no significant elastosis in the UV‐A irradiated mice, and moderate elastosis in the UV‐B irradiated mice. Heavy elastosis was observed when the mice were exposed sequentially to UV‐B and a large dose of UV‐A, but if a moderate dose of UV‐A was given simultaneously with UV‐B, the degree of elastosis was slightly reduced compared with the elastosis induced by UV‐B alone.