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Dermatological aspects of the use of Cyclosporin A for prophylaxis of graft‐versus‐host disease
Author(s) -
HARPER J.I.,
KENDRA J.R.,
DESAI S.,
STAUGHTON R.C.D.,
BARRETT A.J.,
HOBBS J.R.
Publication year - 1984
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1984.tb04662.x
Subject(s) - medicine , graft versus host disease , hypertrichosis , disease , surgery , dermatology
SUMMARY Oral Cyclosporin A (CyA) was given for the prophylaxis of graft‐versus‐host disease (GVHD) to sixty‐seven patients receiving a bone marrow transplant, and was found to be extremely effective in reducing the severity of acute GVHD. Side‐effects of CyA included hypertrichosis, gum hypertrophy, and a rare but serious ‘capillary leak’ syndrome.