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Replication of Paget cells in mammary and extramammary Page?s disease
Author(s) -
PIERARDFRANCHIMONT C.,
PIERARD G. E.
Publication year - 1984
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1984.tb04018.x
Subject(s) - epidermis (zoology) , thymidine , replication (statistics) , paget disease , extramammary paget's disease , medicine , biology , pathology , disease , anatomy , virology , dna , genetics
SUMMARY Replication of Paget cells in mammary and extramammary Paget's disease was evaluated by autoradiography after incorporation of tritiated thymidine. Neoplastic cells proliferated in the deepest layers of the epidermis suggesting a topographical control of their multiplication similar to that of the normal epidermis.