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Topical benzoyl peroxide increases the sebum excretion rate in patients with acne
Author(s) -
CUNLIFFE W. J.,
STAINTON C.,
FORSTER R. A.
Publication year - 1983
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1983.tb07682.x
Subject(s) - benzoyl peroxide , acne , excretion , chemistry , medicine , peroxide , endocrinology , dermatology , organic chemistry , polymerization , polymer
SUMMARY Investigations on fifteen patients with acne showed that at the end of 1 and 2 months of treatment 5% benzoyl peroxide increased the sebum excretion rate by 22.5%. This rise in sebum excretion is probably due to the comedolytic activity of benzoyl peroxide which will influence the pooling of sebum in the upper reaches of the pilosebaceous duct.