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Detection of interferon in the sera of patients with psoriasis, and its enhancement by PUVA treatment
Author(s) -
DIEZEL W.,
WASCHKE S. R.,
SÖNNICHSEN N.
Publication year - 1983
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1983.tb07677.x
Subject(s) - interferon , psoriasis , puva therapy , medicine , immunology , methoxsalen , interferon γ , dermatology , interferon gamma , cytokine
SUMMARY Interferon‐like activity could be detected in the sera of nineteen psoriatic patients (interferon titres between 8 and 64 i. u./ml), whereas healthy controls were negative. Following PUVA treatment the interferon levels increased significantly (interferon titres between 32 and 128 i. u./ml). An enhanced interferon production could explain some of the immunological phenomena connected with PUVA treatment.