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The aetiology of psoriasis: clues provided by benoxaprofen
Author(s) -
ALLEN B.R.,
LITTLEWOOD S.M.
Publication year - 1983
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1983.tb06823.x
Subject(s) - psoriasis , medicine , dermatology , etiology , drug , pharmacology
Summary Twenty‐four patients with psoriasis completed a double‐blind trial of benoxaprofen for their cutaneous lesions. Six out of thirteen on the active drug showed very marked improvement. It is believed that benoxaprofen acts by interfering with the migration of polymorphs into the skin through inhibition of leukotriene B 4 synthesis.