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Direct immunofluorescence in pyoderma gangrenosum
Author(s) -
POWELL F.C.,
SCHROETFR A.L.,
PERRY H.O.,
SU W.P.D.
Publication year - 1983
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1983.tb03966.x
Subject(s) - pyoderma gangrenosum , immunofluorescence , medicine , direct fluorescent antibody , pathogenesis , lesion , pathology , pyoderma , biopsy , dermatology , antibody , immunology , disease
SUMMARY Direct immunofluorescence was done in fifty‐one cases of pyoderma gangrenosum. Biopsy specimens were taken from the peripheral erythematous zone of the lesion. In thirty‐one cases (61%), there was positive immunofluorescence, with perivascular deposition of immune reactants being the most frequent pattern (twenty‐seven cases). These findings support a vasculitic pathogenesis of pyoderma gangrenosum.