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Persisting cholinergic erythema: a variant of cholinergic urticaria
Author(s) -
MURPHY G.M.,
BLACK A. KOBZA,
GREAVES M.W.
Publication year - 1983
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1983.tb03551.x
Subject(s) - cholinergic , rash , medicine , arecoline , erythema , dermatology , trunk , biology , muscarinic acetylcholine receptor , ecology , receptor
SUMMARY A new variant of cholinergic urticaria is described. Four patients each had a similar persistent macular skin rash distributed maximally over the upper limbs and upper trunk. Though the rash was persistent, individual macules were of short duration hut new macules continually appeared at adjacent sites. Exercise and hot baths exacerbated pruritus and provoked lesions in previously unaffected areas. Topically applied benzoyl scopolamine blocked the appearance of the lesions after challenge. Tests of cholinergic function were normal, apart from an exaggerated pupillary response to arecoline in one patient.