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A study of benoxaprofen‐induced photosensitivity
Author(s) -
FERGUSON J.,
ADDO H.A.,
McGILL P.E.,
WOODCOCK K.R.,
JOHNSON B.E.,
FRAINBELL W.
Publication year - 1982
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1982.tb00386.x
Subject(s) - phototoxicity , photosensitivity , action spectrum , sunlight , pharmacology , medicine , in vitro , chemistry , dermatology , photochemistry , materials science , biochemistry , physics , optoelectronics , optics
SUMMARY A study of the abnormal sunlight response seen in nine patients taking benoxaprofen showed that the action spectrum was between 310 and 325 nm, which is similar to the drug's absorption spectrum. In vitro studies using three separate methods indicated that benoxaprofen has a powerful phototoxic action which may be directed mainly against cellular membranes.