Premium
Dyskeratotic degeneration of epidermal cells in pityriasis rosea: light and electron microscopic studies
Author(s) -
OKAMOTO H.,
IMAMURA S.,
AOSHIMA T.,
KOMURA J.,
OFUJI S.
Publication year - 1982
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1982.tb00337.x
Subject(s) - pityriasis rosea , epidermis (zoology) , vacuole , pathology , dermatology , medicine , biology , anatomy , cytoplasm , microbiology and biotechnology
SUMMARY We studied biopsies from twenty‐nine patients with pityriasis rosea. All specimens showed features of subacute or chronic dermatitis as previously reported, but sixteen cases (55%) had dyskeratotic cells within the epidermis. Ultrastructurally, these cells contained an aggregation of tonofilaments, many vacuoles and intracytoplasmic desmosomes. Previously, only non‐speci fic histological changes had been described in pityriasis rosea, but the presence of dyskeratotic cells seems to be a significant feature.