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A fluorescence photographic photometric technique to assess stratum corneum turnover rate and barrier function in vivo
Author(s) -
FINLAY A.Y.,
MARSHALL R.J.,
MARKS R.
Publication year - 1982
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1982.tb00287.x
Subject(s) - stratum corneum , stratum , fluorescence , corneocyte , in vivo , chemistry , barrier function , biophysics , chromatography , pathology , optics , biology , medicine , physics , microbiology and biotechnology , paleontology
SUMMARY A photographic photometric method for objective measurement of fluorescence in skin is described. This method has been used to (a) improve the dansyl chloride method for determining stratum corneum turnover time by making assessments objective and quantitative, and (b) examine the barrier function of the stratum corneum by measuring the concentration of a fluorescent material at different levels within the stratum corneum at different times.