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Direct immunofluorescence on cytological smears in oral pemphigus
Author(s) -
ACOSTA A.E.,
HIETANEN J.,
IVANYI L.
Publication year - 1981
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1981.tb00974.x
Subject(s) - pemphigus , immunofluorescence , direct fluorescent antibody , medicine , dermatology , pathology , immunology , antibody
SUMMARY Direct immunofluorescence was performed on washed oral epithelial smears from thirteen patients with pemphigus vulgaris, thirteen patients with other oral diseases and from ten subjects with clinically healthy oral mucosa. The intercellular deposition of IgG was observed on cytological smears from oral lesions in all patients with active pemphigus. In contrast, smears from pemphigus patients in remission, from patients with other oral diseases and from healthy controls, did not show any fluorescence. Therefore, direct immunofluorescence on cytological smears may be of value in the diagnosis of pemphigus.