Premium
Skin lesions in angioimmunoblastic lymphadenopathy: histological and immunological studies
Author(s) -
BERNENGO M.G.,
LEVI L.,
ZINA G.
Publication year - 1981
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1981.tb00034.x
Subject(s) - erythroderma , pathology , lymph node , lymph , medicine , pathogenesis , dermatology
SUMMARY Angioimmunoblastic lymphadenopathy with dysproteinaemia is reported (AILD) in four patients with different skin pictures. As the disease progresses two main forms predominate: papulonodular and erythroderma. In all cases the histological picture of the skin mirrors that of the lymph‐node. Our results point to an increase in the peripheral blood, lymph‐nodes and skin of T and sub‐sequently of B lymphocytes suggesting that a proliferation of helper T cells and hence activation of the B‐cell subpopulation may be involved in the pathogenesis of some cases of AILD.