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Effect of Gluten‐free diet on recurrent aphthous ulceration
Author(s) -
Walker D.M.,
Dolby A.E.,
Mead J.,
Llewellyn J.,
Rhodes J.
Publication year - 1980
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1980.tb15849.x
Subject(s) - medicine , malabsorption , gluten free , gastroenterology , coeliac disease , biopsy , recurrent aphthous stomatitis , gluten , surgery , dermatology , disease , stomatitis , pathology
Ferguson et al. (1976) found that eight out of thirty‐three patients presenting with recurrent aphthous ulceration (R.A.U.) had jejunal mucosal features of coeliac disease; their oral ulceration remitted on a gluten‐free diet. We have studied eighteen consecutive R.A.U. patients using standard haematological and biochemical parameters of malabsorption, including a xylose tolerance test. Twelve of the patients consented to a jejunal biopsy, following which they were placed on a gluten‐free diet for 3 months. They maintained a daily record of the number of oral ulcers and a daily entry for the pain experienced on a visual analogue chart.