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The effects on rat skin of prolonged exposure to water
Author(s) -
JOLLY M.,
SWAN A. G.
Publication year - 1980
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1980.tb07261.x
Subject(s) - medicine , dermatology
SUMMARY By means of small waterproof chambers held on the backs of rats with adhesive, areas of skin were exposed continuously to sterile distilled water for 1‐, 2‐ and 3‐day periods. All test areas showed discernible changes and many exhibited vesicles, bullae or abscesses in the epidermis. Dermal changes ranged from mild inflammatory cell infiltration to severe oedema and haemorrhagic inflammation.