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Increased chemotactic activity of neutrophil leukocytes in psoriasis
Author(s) -
MICHAËLSSON GERD
Publication year - 1980
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1980.tb07256.x
Subject(s) - psoriasis , chemotaxis , immunology , neutrophile , medicine , inflammation , receptor
SUMMARY The random and active migration of neutrophil leukocytes in agarose was studied in sixty‐one patients with psoriasis and in healthy controls. E. coli filtrate was used as chemoattractant. The random as well as the active migration was increased in psoriasis. The increase was most pronounced in those cases with widespread psoriasis. In twenty patients who were followed for 1–3 years, the neutrophil chemotactic activity remained essentially unchanged.