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Epidermal lipid biosynthesis in acne
Author(s) -
SHUSTER SAM,
COOPER MARY F.,
McGIBBON D.,
WILSON P. D.
Publication year - 1980
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1980.tb06580.x
Subject(s) - dermis , epidermis (zoology) , acne , biosynthesis , lipid metabolism , lipid droplet , biology , sebaceous gland , endocrinology , chemistry , pathology , medicine , dermatology , biochemistry , anatomy , enzyme
SUMMARY Lipid biosynthesis from glucose was increased in severe acne both in dermis and in epidermis which included the top portions of the pilosebaceous follicles. Both tissues retained their characteristic lipid labelling pattern. The magnitude of the increase in dermis and epidermis was similar, suggesting that epidermis may be subject to the same sebotrophic‐lipogenic stimulus which affects sebaceous glands.