Premium
Distribution of glycoproteins containing fucose in normal and psoriatic keratinocytes
Author(s) -
MANN PATRICIA R.,
WILLIAMS R. H.,
GRAY G. M.
Publication year - 1980
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1980.tb06564.x
Subject(s) - fucose , glycoprotein , epidermis (zoology) , psoriasis , cytoplasm , distribution (mathematics) , microbiology and biotechnology , electron microscope , chemistry , cell , biology , pathology , medicine , biochemistry , anatomy , immunology , physics , optics , mathematics , mathematical analysis
SUMMARY Electron microscope autoradiography has been used to compare the fucose‐containing glycoproteins of normal and psoriatic epidermis. Normal keratinocytes and uninvolved psoriatic cells have most of their fucose on the plasma membrane, whereas involved psoriatic cells retain more within the cytoplasm. The fucose distribution in other epidermal cell types is also described.