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A technique for studying the structural detail of isolated human corneocytes
Author(s) -
BARTON S. P.,
KING C. S.,
MARKS R.,
NICHOLLS S.
Publication year - 1980
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1980.tb05673.x
Subject(s) - corneocyte , stratum corneum , layer (electronics) , biophysics , transmission electron microscopy , chemistry , materials science , nanotechnology , biology , pathology , medicine
SUMMARY A technique for the isolation of human stratum corneum cells from any depth within the horny layer is described. Examination of the cells by light, scanning and transmission electron microscope permits a detailed morphological profile of the plasma membrane to be constructed. It is suggested that the technique will be of particular value in determining the effect of chemical agents on the cellular components of the horny layer.