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Serum immunoglobulin values in patients with scabies
Author(s) -
FALK EDVARD S.
Publication year - 1980
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1980.tb05672.x
Subject(s) - medicine , scabies , immunoglobulin e , anti nuclear antibody , antibody , rheumatoid factor , gastroenterology , immunology , dermatology , autoantibody
SUMMARY Serum total IgE levels were found to be increased in thirty‐nine of ninety‐four patients with scabies investigated at the time of clinical presentation. One hundred and fifty‐four patients were found to have a significantly lower serum concentration of IgA during infection than when measured 6 weeks and 9 months following successful treatment (P <0.05). The serum concentration of IgA at 6 weeks and 9 months after treatment did not differ significantly. The serum concentration of IgG during infection was significantly higher than 6 weeks later (P <0.05), and than 9 months later P <0.001). The 6 weeks levels were significantly higher than the results at 9 months (P <0.01). The serum concentration of IgM during infection was higher than 6 weeks later (P <0.1). The 6 weeks levels were lower than those at 9 months (P <0.1), whereas there was no difference between the pretreatment and 9 months levels. No differences were noted in the concentration of C3 and C4. Antinuclear antibodies (ANA) and rheumatoid factor (RF) were not found in any of the patients. In thirty‐two patients with lichen planus no changes in immunoglobulins or complement were observed. This suggests that scabies infection may be associated with a humoral immunological response against the scabies infection.