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Therapeutic evaluation of the oral retinoid Ro 10‐9359 in several non‐psoriatic dermatoses
Author(s) -
A.VIGLIOGLIA PABLO
Publication year - 1980
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1980.tb01662.x
Subject(s) - dermatology , medicine , pityriasis rubra pilaris , ichthyosis , retinoid , tretinoin , psoriasis , retinoic acid , chemistry , gene , biochemistry
SUMMARY Forty‐five patients suffering from various genodermatoses and erythematous, scaling, non‐psoriatic dermatoses were treated orally with the aromatic derivative of retinoic acid, Ro 10‐9359 (Tigason). In the genodermatoses the best results were obtained in ichthyosis, keratodermias and Darier's disease (95.6% good to excellent). Among the erythematous scaling diseases, treatment was effective in lichen planus, parapsoriasis and pityriasis rubra pilaris (53.3% good to excellent results). In comparison with therapies previously employed Ro 10‐9359 was more effective. No serious side‐effects were noted.