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Sézary's syndrome: a clinical evaluation of eight patients
Author(s) -
HAMMINGA L.,
HARTGRINKGROENEVELD C.A.,
VLOTEN W.A.VAN
Publication year - 1979
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1979.tb06201.x
Subject(s) - medicine , university hospital , dermatology , family medicine , library science , computer science
SUMMARY Clinical and laboratory investigations of 8 patients with Sézary's syndrome are presented. Sézary cells were found in peripheral blood as well as in bone marrow and lymph nodes. The overall follow‐up period was 8 years. Different therapeutic regimens were given. The best results were obtained with chlorambucil and prednisone orally, combined with topical application of nitrogen mustard. Three patients died of pneumonia and septicaemia.