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The ribonucleic acid (RNA) skin test in systemic lupus erythematosus and other connective tissue diseases
Author(s) -
JOHANSSON E.A.,
NIEMI K.M.,
HALME H.
Publication year - 1979
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1979.tb05549.x
Subject(s) - connective tissue , connective tissue disease , medicine , dermatology , lupus erythematosus , rna , pathology , immunology , biology , autoimmune disease , disease , antibody , biochemistry , gene
SUMMARY A series of 65 patients with different autoimmune diseases was examined using different RNA‐solutions for intradermal skin tests. Clinically positive results were obtained most often in patients with mixed connective tissue disease but quite often also in patients with systemic lupus erythematosus and progressive systemic sclerosis or with some symptoms of an autoimmune nature. The histological examination of the biopsies from the test sites revealed that there was no correlation between the clinically positive tests and the histological criteria usually used as a sign of a positive test.