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Co‐existence of pemphigus, anti‐skeletal muscle antibody and a retroperitoneal paraganglioma
Author(s) -
McKEE P.H.,
McCLELLAND M.,
SANDFORD J.C.
Publication year - 1978
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1978.tb06185.x
Subject(s) - pemphigus vulgaris , pemphigus , medicine , myasthenia gravis , paraneoplastic pemphigus , thymoma , malignancy , pathology , polymyositis , antibody , dermatology , autoantibody , immunology
SUMMARY Occasional reports have appeared in the literature describing a relationship between pemphigus vulgaris and malignaney (Krain & Bierman, 1974; Krain, 1974; Tagami et al. , 1976). Carcinoma of the ovary, stomach, breast, endometrium and bronchus have all been associated with pemphigus (Krain, 1974). The association between pemphigus and thymoma is well known (Stillmand & Baer, 1972). Pemphigus has also been described in connection with various lymphoproliferative malignancies (Naysmith & Hancock, 1976). The purpose of this paper is to describe a patient who suffered from a rare retroperitoneal tumour in association with pemphigus vulgaris. His serum contained a high titre of anti‐skeletal muscle antibody, although he showed no clinical manifestations of myasthenia gravis. He also had immunological manifestations suggestive of lupus erythematosus.