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A quantitative approach to epidermal wound healing: the effect of dexamethasone on regenerating epithelium
Author(s) -
DEVITT H.,
CLARK M.A.,
MARKS R.,
PICTON W.
Publication year - 1978
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1978.tb06158.x
Subject(s) - dexamethasone , acanthosis , epithelium , regeneration (biology) , epidermis (zoology) , wound healing , suction blister , medicine , biology , chemistry , pathology , endocrinology , microbiology and biotechnology , anatomy , surgery , hyperkeratosis
SUMMARY The effect of dexamethasone on the regeneration of new epithelium over the base of an excised suction blister has been studied over a period of 9 days. It was found that dexamethasone did not significantly affect the migration of epidermis over the blister base but it did significantly reduce the number of cells in DNA synthesis and post wounding acanthosis of wound edge and regenerating epithelium.