Premium
Generalized Hailey‐Hailey disease
Author(s) -
MARSCH WOLFGANG CH.,
STÜTTGEN GÜNTER
Publication year - 1978
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1978.tb02024.x
Subject(s) - university hospital , medicine , dermatology , library science , family medicine , computer science
SUMMARY A woman of 60 developed a generalized erythroderma. The case history revealed classical symptoms of Hailey‐Hailey disease for 17 years. Light‐ and electron microscopic investigations confirmed the diagnosis of generalized Hailey‐Hailey disease—an extremely rare condition. Two additional cases with widespread clinical manifestations are presented. These observations underline the fact that the whole epidermis is genetically disturbed and may react to various insults with suprabasal acantholysis.