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HLA antigens in persistent palmoplantar pustulosis and its relationship to psoriasis
Author(s) -
WARD JOANNA M.,
BARNES R. M. R.
Publication year - 1978
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1978.tb02013.x
Subject(s) - palmoplantar pustulosis , pustulosis , psoriasis , incidence (geometry) , dermatology , medicine , human leukocyte antigen , immunology , antigen , osteitis , osteomyelitis , physics , optics
SUMMARY HLA typing was performed on 93 patients with persistent palmoplantar pustulosis. The incidence of either HLA B 13 or BW 17 was not significantly increased as compared to controls. In addition the frequency of BW 35 was no different from controls. However, the present results document a significantly increased frequency (38.7%) of B8. Taken together these data are good evidence that palmoplantar pustulosis is a genetically distinct disease entity from psoriasis vulgaris, despite the increased incidence of psoriasis in the condition.