Premium
Cellular immunity to P. acnes in the normal population and patients with acne vulgaris
Author(s) -
GOWLAND G.,
WARD R. M.,
HOLLAND K. T.,
CUNLIFFE W. J.
Publication year - 1978
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1978.tb01959.x
Subject(s) - acne , immunity , cellular immunity , cell mediated immunity , inflammation , medicine , immunology , population , cord blood , immune system , dermatology , environmental health
SUMMARY Patients with varying degrees of acne, acne‐free adult controls and samples of cord blood were investigated for cell mediated immunity to P. acnes using a leukocyte migration inhibition test. Despite the fact that the mean migration index tended to decrease with acne severity, only the patients with severe acne showed cell‐mediated immunity. It is suggested that when cellular immunity arises it is a late event which may contribute to inflammation but is probably not a factor in its initiation.