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Pathogenicity of the intercellular antibodies of pemphigus and their periodic removal from the circulation by plasmapheresis
Author(s) -
RUOCCO V.,
ROSSI A.,
ARGENZIANO G.,
ASTARITA C.,
ALVIGGI L.,
FARZATI B.,
PAPALEO G.
Publication year - 1978
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1978.tb01630.x
Subject(s) - plasmapheresis , pemphigus , antibody , titer , intracellular , immunology , medicine , biology , biochemistry
SUMMARY The authors are convinced that the intercellular antibodies of pemphigus are pathogenic. Consequently periodic plasmapheresis in two patients with pemphigus has been performed to remove the antibodies from the circulation. After larger plasma‐exchanges there was a decrease of the antibody titre and a parallel improvement of the clinical condition.