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Elevated serum IgE and IgG 4 in patients with atopic dermatitis
Author(s) -
SHAKIB F.,
McLAUGHLAN P.,
STANWORTH D. R.,
SMITH E.,
FAIRBURN E.
Publication year - 1977
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1977.tb15428.x
Subject(s) - atopic dermatitis , immunoglobulin e , medicine , dermatology , immunology , antibody
SUMMARY The quantitative measurement of the IgE and IgG subclass levels in the sera of 29 patients with atopic dermatitis has revealed significantly elevated levels of IgE and IgG 4 in a relatively high proportion of patients with this condition compared to non‐atopic patients with warts and to a group of normal volunteers studied previously. The possible significance of these observations is discussed in relation to current evidence suggesting the involvement of IgG4 in certain immediate‐type hypersensitivity disorders.