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An acne‐free naevus
Author(s) -
CUNLIFFE W.J.,
EAD R.D.,
PERERA W.H.D.,
HODGINS M.B.
Publication year - 1977
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1977.tb06139.x
Subject(s) - acne , dermatology , medicine , free testosterone , dihydrotestosterone , sebaceous gland , testosterone (patch) , endocrinology , androgen , hormone , sex hormone binding globulin
SUMMARY Investigation of rare disorders may sometimes help in the understanding of common problems. We describe a patient with an unusual and previously unreported acne‐free naevus occurring in an area severely affected by acne. Investigation revealed smaller sebaceous glands, a reduced sebum excretion rate, decreased number of Corynebacterium acnes in the pilosebaceous ducts and a reduced conversion of testosterone to 5 αdihydrotestosterone in the areas which were free of acne compared with acnebearing skin. The results of these investigations support some of the suggested mechanisms responsible for the development of acne.