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Lupus erythematosus profundus (Kaposi‐Irgang) with monoclonal gammopathy
Author(s) -
FEUERMAN ELEASAR J.,
HALEVY SIMA
Publication year - 1977
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1977.tb05190.x
Subject(s) - monoclonal gammopathy , medicine , dermatology , lupus erythematosus , discoid lupus erythematosus , gammopathy , connective tissue disease , pathology , disease , monoclonal , autoimmune disease , monoclonal antibody , immunology , antibody
SUMMARY The appearance of subcutaneous nodules of lupus erythematosus profundus on the face and neck of a woman with a long history of lupus erythematosus (LE) is reported. Of note were the three distinct stages in the course of the disease: (i) discoid LE, first appearing at the age of 42; (2) systemic LE, appearing 10 years later; (3) LE profundus, appearing 21 years after the diagnosis of discoid LE was made. The finding of monoclonal gammopathy is of particular interest, although its relationship to the basic disease has not been clarified.