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Immunological aspects of psoriasis
Author(s) -
GUILHOU JEANJACQUES,
CLOT JACQUES,
MEYNADIER JEAN,
LAPINSKI HELENE
Publication year - 1976
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1976.tb05137.x
Subject(s) - psoriasis , immunoglobulin e , immunology , antibody , medicine , immunoglobulin a , immune system , immunoglobulin g , saliva
SUMMARY Sixty patients with psoriasis have been studied for quantitative estimation of serum immunoglobulin A, G and M (60 cases), immunoglobulin E (43 cases), salivary immunoglobulin A (28 cases) and anti‐IgG factors in the serum (40 cases). All the data have been statistically compared to a large control group (300 subjects). The results show an increase of the serum IgG and IgA means, an increase of salivary IgA which is correlated with the serum IgA, an increase of IgE levels in some patients and the presence of anti‐IgG activity in the serum of 45% of patients with psoriasis. All these findings are statistically significant when compared to controls. These data could be in favour of auto‐immune processes in psoriasis.