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Prostaglandins and pruritus *
Author(s) -
LOVELL C.R.,
BURTON PATRICIA A.,
DUNCAN ETHEL H.L.,
BURTON J.L.
Publication year - 1976
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1976.tb04383.x
Subject(s) - medicine , dermatology
SUMMARY We have found that pretreatment of human skin with prostaglandin El significantly lowers the threshold of human skin to itching evoked by both histamine and papain. Prostaglandins may thus potentiate pruritus in inflammatory skin disease, presumably by a non‐specific effect on nerve‐endings.