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Contact urticaria and anaphylactoid reaction induced by topical application of nitrogen mustard
Author(s) -
GRUNNET EVA
Publication year - 1976
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1976.tb04350.x
Subject(s) - nitrogen mustard , mycosis fungoides , medicine , dermatology , contact urticaria , contact dermatitis , allergy , surgery , chemotherapy , immunology , cyclophosphamide , lymphoma
SUMMARY A 36‐year‐old woman and a 16‐year‐old boy, both suffering from mycosis fungoides, developed urticaria and an anaphylactoid reaction after topical whole body application of nitrogen mustard. Prick tests with nitrogen mustard solution produced a weal and flare response. Both patients had previously been treated intermittently with total body applications of nitrogen mustard for 2½ years and 1 year respectively without complications.