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Paroxysmal itching in multiple sclerosis
Author(s) -
OSTERMAN P.O.
Publication year - 1976
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1976.tb00869.x
Subject(s) - itching , multiple sclerosis , medicine , carbamazepine , lesion , dermatology , surgery , epilepsy , immunology , psychiatry
SUMMARY In three women with multiple sclerosis, paroxysmal attacks of itching occurred. There were several similarities between these attacks and other types of paroxysmal phenomena previously described in multiple sclerosis. The attacks were brief, but usually lasted several minutes, they started and ended abruptly, and recurred several times a day. They were controlled effectively by carbamazepine. It is suggested that paroxysmal itching is caused by transversely spreading ephaptic activation of axons with‐in a partially demyelinated lesion in pain‐conducting fibre tracts in the central nervous system.