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The use of thin layer chromatography in the separation of free porphyrins and porphyrin methyl esters
Author(s) -
SMITH S.G
Publication year - 1975
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1975.tb06494.x
Subject(s) - porphyrin , welsh , thin layer chromatography , chemistry , chromatography , medicine , library science , organic chemistry , history , computer science , archaeology
SUMMARY Thin layer chromatographic techniques for the separation and subsequent quantification of free porphyrins, coproporphyrin isomers and the methyl esters of porphyrins are described including a 2‐dimensional system. The relevant RFs for a wide range of porphyrins are given. These methods have been in use in Cardiff and Barcelona for a number of years and were used in the survey of cases described by Piñol et al. (1975) which resulted in the discovery of the new porphyria, hepato‐erythrocytic porphyria.